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Plus, dosing levels are typically titrated and increase more gradually over several weeks of time to minimize unwanted gastrointestinal side effects

Our results showed general safety of LipRSV, except for mixed liposomes, which caused hemolysis

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Expression microarray analysis demonstrated that the significantly downregulated genes were CYP3A4, CYP3A7, UGT2B11 and UGT2B15 in MC tissue, and western blotting and immunofluorescence analyses indicated that the expression of CYP3A4 in normal tissue was higher than that in MC