glp 1 gip mechanism of action Targeting GLP-1, & GCG in Obesity and Type 2 Diabetes Research Biology of Incretins: GLP-1 and

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Its appetite-suppressing and weight-reducing properties have shown effectiveness in obesity management, though its use in reversing weight gain related to cancer therapies is another potential benefit

The most cited single result is from Yun and colleagues in 2018, who showed that NLY01, a long-acting PEGylated GLP-1R agonist, blocked the microglia-driven conversion of resting astrocytes into the neurotoxic A1 phenotype in mouse models, a process implicated in neuronal death in both Parkinsons and Alzheimers disease [4]

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