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As noted in the slide bioavailability was high at 79% but there is a small reduction and delay in absorption when taking the medication with food
Terpstra M, Henry PG, Gruetter R
Samples were reconstituted in 100 l 50% acetonitrile (aq) before centrifugation at 300 g
[ref] In summary, knowing your risk factors may help you figure out whether acetaminophen is a safe choice for you as a pain reliever when using it at higher doses or for longer periods of time
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