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A dual agonist such as tirzepatide engages both the GLP-1 and GIP receptors, adding a second incretin mechanism
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Due to (temporarily) reduced sodium reuptake while continuously promoting glucosuria, these drugs induce a reduction in GFR likely via activation of tubuloglomerular feedback (TGF) that may represent reduced intraglomerular pressure [5]
Storage method: In a cool dry place at a temperature not exceeding 25 degrees
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