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It is often preferred by patients who want a gentler physiologic shift or who experience difficulty tolerating the stronger gastrointestinal effects associated with higher-potency GLP-1 agents

Three RCTs were of short duration ranging from 12 to 26 weeks and one RCT had a 26-week main study phase [34] with a 26-week extension phase [35], thus the data for the main phase of the study was used for meta-analysis to minimize the heterogeneity

Certainly, if youve already had NAION or a history of blindness, youll want to consider the risks and be cognizant of the symptoms of NAION, which is painless vision loss, she says.

Taking your dose on the same day every week helps maintain that steady state in your blood