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An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]
It does not cause big changes in other pituitary hormones
That alone makes the comparison with retatrutide less direct than it may seem at first glance
If a supplement has low bioavailability, your digestive system might break it down or flush it out before it can do its job
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