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NGFRs nerve growth factor receptors acetyl L-carnitine is clinically used to treat depression associated with the primary degenerative disease (Alzheimer's Dementia), is also prescribed to treat the secondary degenerative disease (vascular dementia), and is a broad-spectrum agent which can be used as a first-selective drug ex hibiting excellent ameliorating effects on early- stage dementia patients (The Journal of Applied Pharmacology (2001) 9:285-290)

Primary markers include IGF-1, fasting insulin, and targeted metabolomic panels evaluating oxidative phosphorylation byproducts