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The aromatase gene is directly regulated by CREB (107), and this enzyme converts androgens (e.g., testosterone) to estrogens, while StAR mediates the transport of cholesterol substrate to the mitochondria for synthesis of testosterone, E2 and P4 in steroidogenic cells (Figure 2)
Phenotypically, we found that the intervention with AcM led to an increased NR and BWG across all treatments whilst also noticing a significant linear relationship between these two variables
Additionally, individuals experiencing significant changes in their bowel habits should be particularly vigilant
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