As the direct reaction species to react with Si-based agent is hydroxide ions, the higher the pH of the reaction solution, the greater the amount of hydrogen generated from Si-based agent
Meth Psych
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[1] [6] Severe deficiencies may include symptoms of reduced heart function, suppression of bone marrow, as well as more various severe neurological symptoms possibly including sensory loss, abnormal balance and reflexes, memory and consciousness impairment, smell and taste problems, depression, irritability, confusion, and psychosis