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HPLC determination of carnitine and acylcarnitines in human plasma by means of fluorescence labeling using 2-(4-hydrazino-carbonylphenyl)-4,5-dipenylimidazole
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John found that exenatide is an analog of human GLP-1RA, with 53% homology to human GLP-1RA
The FDA's 2003 guidance on pharmacokinetics in patients with impaired hepatic function acknowledges that drugs primarily cleared by non-hepatic mechanisms may not require dedicated hepatic impairment studies [5]
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