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One more clinical note: the trial used a gradual titration protocol specifically to manage tolerability
GLP-1 may impact IBD through several mechanisms, including the modulation of T-cell maturation and activity, adjustment of innate immune cell populations, like macrophages and DCs, suppression of inflammatory cytokines generation, and enhancement of tissue repair in damaged epithelium [220]
Sfikas G, Psallas M, Koumaras C, Imprialos K, Perdikakis E, Doumas M, et al
This metabolic reset can be taxing
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