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Tirzepatide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis
It does not require a prescription for research use, but individuals considering self-administration should understand they are operating outside clinical oversight and assuming the full risk of unknown adverse effects
Patient monitoring for potential adverse effects like gastrointestinal disturbances, hypoglycemia, and injection site reactions is essential during treatment with GLP-1 agonists
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