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doi:10.1046/j.1365-2125.1999.00898.x Patient Safety: Polypharmacy in Vulnerable Older Adults: Why, Who, When, What, and How to Safely Deprescribe Learning Objectives After completing this knowledge-based continuing education activity, pharmacists will be able to Describe the risk of suboptimal medication use, including polypharmacy, in frail, older populations Recognize facilitators and barriers when managing polypharmacy Identify instances of inappropriate polypharmacy Apply an action plan for meaningful deprescribing After completing this knowledge-based continuing education activity, pharmacy technicians will be able to Describe polypharmacy and its impact on frail, older population Recognize facilitators and barriers when managing polypharmacy Identify recommended strategies for deprescribing Infer when to refer patients for action plans to implement meaningful deprescribing Release Date: Release Date: July 15, 2025 Expiration Date: July 15, 2028 ACPE UANs Pharmacist: 0009-0000-25-049-H05-P Pharmacy Technician: 0009-0000-25-049-H05-T Session Codes Pharmacist: 25YC49-HLK Pharmacy Technician: 25YC49-KHL Accreditation Hours 2.0 hours of CE Accreditation Statements Disclosure of Discussions of Off-label and Investigational Drug Use The material presented here does not necessarily reflect the views of The University of Connecticut School of Pharmacy or its co-sponsor affiliates

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Medical Evidence on Dose Splitting and Semaglutide Safety No randomized controlled trials have directly compared once-weekly semaglutide injections to split-dose protocols, meaning the safety and efficacy of dose splitting remain unknown from a clinical evidence perspective