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This would contradict the hypothesis of the role of peroxynitrite as the key oxidant in APAP pathophysiology and would also be inconsistent with the limited LPO
doi: 10.1002/jcb.v120.12 95 BenakisCSimatsATritschlerSHeindlSBesson-GirardSLloveraGet al
Metab Clin Exp
The standard titration approach The clinical trials used specific escalation protocols designed to minimize GI disturbance while still reaching therapeutic dose levels
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