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As the understanding of the genetic underpinnings of AGA continues to grow, so too does the potential for more refined, personalized treatments

Although not involved in CoA metabolism, the biotinidase enzyme, which is involved in the release of biotin from protein to which the vitamin is covalently bound, is also a member of the vanin family of enzymes

Nanoparticle-based delivery of VitE or other OxLDL scavengers could enhance the specificity and efficacy of this approach, enabling sustained modulation of CAF metabolism within the TME

Alvarez XA 1 , Laredo M, Corzo D, Fernndez-Novoa L, Mouzo R, Perea JE, Daniele D, Cacabelos R