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Providers should monitor weight trajectory , GI tolerability (nausea, vomiting, constipation) , signs of pancreatitis (persistent severe abdominal pain vomiting), gallbladder disease (RUQ pain, fever, jaundice), hydration/renal function when clinically indicated (risk of AKI with severe GI effects), blood pressure , and glucose metrics (especially if combined with insulin or sulfonylureas due to hypoglycemia risk)

Rare systemic effects have also been observed in experimental models

Abstract The metabolic principles underlying the differences between follicular and marginal zone B cells (FoB and MZB, respectively) are not well understood