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Reductase enzymatic activity The reductase activities of the WT and mutant (K8A, C20A and K47A) proteins were measured spectrophotometrically by recording the increase in absorbance at 260 nm using a UV-VIS spectrophotometer (UV-1800, Shimadzu, Kyoto, Japan) as described previously 37

Typowe dawki eksperymentalne to rzdu mikro- lub miligramw na kilogram masy ciaa, z reguy w zakresie od 1 mcg/ml do kilku mg/kg, ale precyzyjne dawkowanie powinno by dostosowane do konkretnej terapii i wskaza

Strikingly, the study revealed that the immune cells of these patients act as an "energy sink." In a desperate attempt to survive the overwhelming oxidative stress, the immune cells upregulate their own intracellular glutathione production

Any further discrepancies were resolved through third-reviewer adjudication