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Several animal studies, including the following have supported the benefit of CoQ10 treatment in ALS: In an animal model of familial ALS, administration of coenzyme Q10 significantly extended life span and oral administration significantly increased CoQ10 concentrations in the brains and mitochondria of the test animals (Matthews 1998)
Pregnant or breastfeeding individuals should avoid glutathione IV therapy since research on safety during these times is limited
Some protocols even use 5mg twice weekly for the first two weeks, then drop to the maintenance schedule below
These persistence patterns reflect a combination of factors, including side effects, cost barriers, and the chronic nature of obesity treatment, and have important implications for projecting long-term cost offsets and population health outcomes
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