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Tree-based ensemble survival methods were selected a priori for favorable biasvariance characteristics under moderate sample sizes, robustness to multicollinearity and the ability to model nonlinear effects without parametric assumptions or temporal interpolation

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Lilly's tirzepatide achieved up to 15.7% weight loss in adults with obesity or overweight and type 2 diabetes in SURMOUNT-2

To quantify the number of cells in active mitosis, extruded germlines were stained with an anti-pH3 antibody (Rabbit-monoclonal anti-pH3 Sigma Aldrich 06570 (clone H3S10P) - 1:1000) and pH3-positive nuclei counted