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Biosimilar applications already filed in China, India, and Europe hint at mid-to-late-decade competitive pressure, but originators retain exclusivity around key once-weekly and oral formulations that will support premium pricing in the near term
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Ghirardi, A
A peer-reviewed study in the Journal of Endocrinology confirming that AOD9604 produces lipolysis and increases fat oxidation in obese mice via the beta-adrenergic pathway, with effects comparable to full-length HGH but without the insulin-disrupting side effects provided early mechanistic validation that informed the human trials
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