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GLP-1s have emerged as a promising treatment to halt or even reverse the effects of NAFLD, largely due to the effects on weight loss and insulin secretion, but there is increasing evidence that GLP-1s may have more direct effects on the liver and benefits in the treatment of NAFLD

Hexarelin's GHS-R1a activity means it activates a different intracellular signaling cascade, stimulates ACTH and prolactin co-secretion, and has known tachyphylaxis kinetics

MASH, metabolic dysfunction-associated steatohepatitis

Not only was it found to reduce total fat mass and increase muscle mass, but it also helped decrease fatigue and improve cognitive function