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When to stop Stop the protocol and contact your provider if you experience persistent redness or swelling at injection sites beyond 72 hours, fever, or any systemic symptom that does not correlate with the expected mild post-injection reaction

Value of both clinical trials and real-world data studies Both the SURMOUNT-5 clinical trial and Truveta Researchs real-world evidence study reinforce the same key trend: tirzepatide-based medications consistently outperform semaglutide-based medications for weight loss in patients with overweight or obesity

The constipation burden appears lower with retatrutide

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