semaglutide and lymphedema GLP-1 for Lymphedema: Can It Help Reduce Swelling? Is GLP-1 Good for Lymphedema?

In large studies, GLP-1 therapies reduced body weight by an average of 4.57 kg, body mass index by 2.07 kg/m, and waist circumference by 4.55 cm compared with placebo

The same study confirmed dose-dependent increases in GH without significant changes in other pituitary hormones (prolactin, TSH, LH, FSH, cortisol), supporting its selectivity for the GH axis

Side effects and what they mean for your results GI side effects are the main reason people discontinue retatrutide, and discontinuation is the primary reason real-world results fall short of trial outcomes

Read our step-by-step guide to help you make the right decision.