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Through the addition of a fatty acid side chain, an acidic gamma-Glu group, and lipophilic 2xOEG groups, the molecule can bind more securely to plasma albumin, thereby reducing its glomerular ltration rate4
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How much body weight actually moves depends on the specific compound, the dose, adherence, and individual factors, and FDA-approved weight-management dosing is titrated upward from a starting dose over several weeks according to each product's label
The minimum effective dose for type 2 diabetes in the SUSTAIN program was 0.5 mg
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