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The placebo, designed to mimic the taste of L-carnitine, was chosen to control for any psychological effects that may arise from knowing whether the participant was receiving the active supplement or a non-active substance

Clinical studies showed that participants using the medication lost a significant percentage of their body weight compared to those using a placebo

The first-line nod was given based on data from the Phase III KEYNOTE-859 study, where the Keytruda-based regimen cut the risk of death by 22% versus chemotherapy alone