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Semaglutide also suppresses glucagon release, slows gastric emptying, and acts on appetite centers in the brain to promote satiety
We use variants of the peptides GLP-1 and exendin-4 (Ex4) to explore the interplay between helical propensity near the agonist N terminus and the ability to bind to and activate the receptor
A 5 mg dose of one does not produce the same clinical effect as 5 mg of the other
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