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consider for patients with pre-existing liver disease, hepatic risk factors, or when starting antidepressants with specific hepatic cautions (e.g., duloxetine in patients with risk factors) Periodic monitoring follow the mandatory schedule for agomelatine (baseline, 3, 6, 12, and 24 weeks)
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Anticoagulant medications, compression stockings, increased movement, thrombolytic therapy (clot dissolvers), or surgical intervention may be required to treat DVT or PE
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