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Indeed, in pre-clinical models, retatrutide, a triple agonist (GLP-1/GIP/glucagon), resulted in greater WL and improved glucose profile compared to tirzepatide through increased energy expenditure and reduced calorie intake [80, 81]

These treatments permanently reduce fat cells in areas that are resistant to diet and exercise, helping refine contours and enhance overall shape

Fans got a small glimpse into this side of the tennis star's journey in her 2018 HBO documentary Becoming Serena

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