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Allergic reactions (rare), such as rash, itching, or swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing

Results: Several studies have discussed the CV beneficial effects of GLP-1 RAs in terms of reducing blood pressure, lipid levels, body weight, risk for arrhythmias, reducing the risk of major adverse CV events, and hospital admission for heart failure

Regulatory authorities require ongoing pharmacovigilance, including periodic safety update reports from the manufacturer

In rodents, the GLP-1 receptor expression level on thyroid C cells is high, whereas in humans, the expression of the receptor is lower