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Previous investigations on mutant SOD1 transgenic mice revealed pathogenic processes in motor neurons, including protein misfolding, mitochondrial malfunction, and neurofilament buildup (Zhou et al., 2023)
For metabolomics analysis, small pieces of tissue (~ 10 mg) were cut, weighed and collected in separate tubes
They reduce severity but do not eliminate risk
Our bodies produce free radicals as byproducts of cellular reactions, metabolism of foods, breathing and other vital functions
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