glp 1 camp GLP-1 in the Hypothalamic Paraventricular Nucleus Promotes Sympathetic Activation and Hypertension semaglutide #glp1 #gpcr #bioassay #type2diabetes

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doi: 10.1056/NEJMcp2102062 233 DaviesMFrchLJeppesenOKPaksereshtAPedersenSDPerreaultLet al

Upper endoscopy (with duodenal biopsy), ultrasound, CT scan, 2 stool tests, and a plethora of bloodwork

Participants with renal impairment were excluded if they had previously undergone renal transplantation or had unstable renal function or acute exacerbation of renal disease within 14 days of baseline, as indicated by recent history or worsening of clinical or laboratory signs