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Intranasal administration is valued as a non-invasive means of both systemic and local administration with good bioavailability, rapid onset, and targeted effects on the central nervous system [13, 14]
G., Clemens, R
When PLOOH is not rapidly neutralized as an PLOH by glutathione peroxidase 4 (GPX4) in time, PLOOH further reacts with ferrous ions, and the resulting lipid radicals, such as alkoxyl phospholipid radicals (PLO) and PLOO, react with PUFA-PLs (8)
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