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The SURMOUNT-1 trial showed participants losing up to 22.5% of their body weight on the highest dose of tirzepatide, while STEP 1 trial data for semaglutide showed average losses around 14.9%

Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications that mimic the action of naturally occurring GLP-1, an incretin hormone produced in the intestinal tract

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