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A yellow oval in Panel B indicates that the enzyme is affected by estradiol and/or testosterone, and therefore, its activity is different in females than males

Key Point: Important Update: FDA Ruling on Compounded GLP-1s As of March 2025, the FDA has declared the shortages of semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) to be resolved