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Adjusted Model adjusted for covariates included age, gender, ethnicity, BMI, ratio of family income to poverty, smoking status, alcohol use, urine albumin, and urine creatinine
Endotoxin (USP ) The Bacterial Endotoxins Test, performed using the LAL (Limulus Amebocyte Lysate) method, quantifies endotoxin contamination in endotoxin units per milliliter (EU/mL)
Phase Tirz escalation 1 Weeks 5-8 Tirzepatide 5.0 mg/week Cagrilintide Not started Notes Continue tirzepatide alone
Investigators also collected serial blood samples to track shifts in lipids, C-reactive protein, and liver enzymes, providing a broader picture of metabolic health
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