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Only 4.3% of participants discontinued treatment entirely due to gastrointestinal side effects
It also inhibits matrix metalloproteinases (MMPs), enzymes that degrade ECM, preserving skin structure
To assess its potential use as an anti-obesity treatment, Novo Nordisk funded the Semaglutide Treatment Effect in People with Obesity (STEP) clinical trial program
The FDA labeling also includes important warnings about risks of pancreatitis, acute gallbladder disease, and a boxed warning regarding thyroid C-cell tumors
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