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The intertwined roles of PERK and IRE1 in angiogenesis, EMT, dormancy, and therapy resistance emphasize why indiscriminate UPR inhibition is unlikely to succeed clinically and why pathway-selective, context-aware strategies are needed
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M., Thorburn, D., and Chinnery, P
(PubMed) Giacosa A, Faliva MA, Perna S, Minoia C, Ronchi A, Rondanelli M
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