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Although there is no evidence that PYY can directly influence insulin secretion in humans (53), activation of Y1 receptors is associated with increased intestinal motility and orexigenic effects, while conversely, Y2 receptor activation mediates the enterogastrone and anorectic effects of PYY (54)
However, it is important to note the heterogeneity observed in some of the outcomes, particularly for BMI and body weight reductions
Keep a symptom diary: note how you feel each day it helps guide medical decisions
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