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The duration guide for semaglutide provides useful context for understanding this pattern, as the underlying biology is similar across the class
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It is most associated with SGLT2 inhibitors (a different class of diabetes drug) but has been reported with GLP-1 medications in the context of very low carbohydrate intake, particularly during illness, fasting, or periods of very low food intake
Beyond glycaemic control, Ozempic has been shown in clinical trials (SUSTAIN-6) to reduce cardiovascular events in people with type 2 diabetes and established cardiovascular disease, although this is not a separate licensed indication in the UK
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