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The cardiovascular and kidney outcome trials involved years of follow-up and showed benefit rather than harm

prednisolone) cause fluid retention and increased appetite Some antidepressants particularly mirtazapine, amitriptyline, and some SSRIs Antipsychotic medications associated with significant weight gain Insulin and sulphonylureas can promote weight gain in type 2 diabetes management Beta-blockers and some antihypertensives If you are taking any of these medications, discuss with your GP or prescriber whether alternatives exist or whether your weight loss target should be adjusted accordingly

Apovian says those tend to go away after a few weeks

Approved Uses of PT 141 for Women The FDA approved Vyleesi for one specific use in women