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As noted above, mTOR signaling has emerged as a key control point for B cell functions 35

Moreover, this compound can facilitate recovery from injuries

Additionally, GLP-1 therapy may increase serum uric acid levels through weight loss-related purine metabolism shifts, further elevating nephrolithiasis risk in susceptible individuals

Importantly, these phenotypes contrast with the non-inducible liver-specific Gclc KO mouse strain ( Gclc f/f Albumin-Cre), which develops liver failure and dies shortly after birth 30