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The corresponding IC50 values for the oxazole derivative 46 with the extended P1 side chain were 35 and 57 nM, respectively (Kokkala et al., 2016)
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Primary carnitine deficiency (carnitine deficiency, systemic primary: CDSP) is an autosomal recessive disorder that results from the lack of function of the carnitine transporter, OCTN2
This chelation function is particularly important given the ubiquitous nature of heavy metal exposure in modern environments
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