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The -oxidation reaction (as well as the remainder of the reactions of phytanic acid oxidation) occurs within the peroxisomes and requires a specific -hydroxylase (specifically phytanoyl-CoA hydroxylase, PhyH), which adds a hydroxyl group to the -carbon of phytanic acid
Deficiency can cause numbness, tingling, and cognitive fog
Practically, that means a few things to watch
Unlike other GH secretagogues, ipamorelin very surprisingly does not induce a significant increase in adrenocorticotropic hormone (ACTH) or cortisol
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