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Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease
Most GLP-1RAs, aside from a new oral formulation of semaglutide (Rybelsus tablets), are administered subcutaneously via pen-like devices (once daily to once weekly) due to poor oral bioavailability, and all are renally excreted 1
Archives of Internal Medicine, 130(5), 778-780
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