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Indeed, 4-en-VPA is transformed through -oxidation to reactive intermediates such as 2-propyl-2, 4-pentadienoic acid (2, 4-dien-VPA) that are capable of depleting mitochondrial GSH, as suggested by rat studies [60]
GLP-1 medications reduce appetite and slow gastric emptying, creating a prolonged feeling of fullness and leading to fewer calories consumed throughout the day
EMBO J (1991) 10:224758
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