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Luersen K, Walter RD, Muller S (2000) Plasmodium falciparum infected red blood cells depend on a functional glutathione de novo synthesis attributable to an enhanced loss of glutathione
Nitric oxide synthase (NOS) requires NADPH as a cofactor to produce NO
This provides the possibility of a glutathione (G-SH) substitution for the intracellular space, without an endogenous glutathione biosynthesis which is still possible depending on the degree of cell damage being inhibited or blocked by means of competitive and / or allosteric inhibition
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