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By co-delivering chemotherapeutic agents that induce ICD with immunomodulators that reprogram the TME, these platforms can achieve synergistic antitumor effects that are not attainable with either modality alone (43, 61)
Gastroenterology 143, 765776.e3
That drop does not happen gradually
[1] [7] Other notable effects include injection site reactions beyond pain (erythema, pruritus, induration in 13% of patients), increased heart rate (particularly with liraglutide), gallbladder disease (including gallstones and cholecystitis), and potential dehydration-related acute kidney injury
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