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New England Journal of Medicine , 384 (11), 9891002
The 1st glutathione-interaction site, also termed glutathione-scaffold site, is rather well defined and comprises several protein areas that altogether contribute to catalysis by interacting with the glutathione moiety of GSSR 7,8,13,14,15,35 , therefore explaining the specificity for the -glutamyl moiety 9,49,50
The question is whether enough experts and officials ultimately agree that GLP-1s will offer a shortcut equivalent to substances like diuretics, which are pills that cause the kidneys to put extra salt and water into urine
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