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Therapeutic strategies for neurodegenerative disorders have commonly targeted individual pathological processes

126 The PI3K/Akt pathway is pivotal, where insulin activation phosphorylates phosphatidylinositol 4,5-bisphosphate via PI3K to produce phosphatidylinositol 3,4,5-triphosphate, triggering Akt

Among the 600 participants enrolled in the trial, 155 received placebo, 145 received tirzepatide 5 mg, 152 received tirzepatide 10 mg, and 148 received tirzepatide 15 mg