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Without adequate glutathione to support detoxification, these toxic Phase I intermediates would accumulate, causing massive oxidative stress, mitochondrial dysfunction, and ultimately, severe liver damage
You recommend adequate calcium and vitamin D intake through diet and supplements, balance training and weight-bearing exercises, and pharmacotherapy with an oral bisphosphonate
The secondary endpoints included changes in body weight and fasting plasma glucose
In contrast, the impact is smallest in the oldest age group (85+), where uptake falls and the scope for benefit narrows
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